Considering Pramlintide Therapy for Postprandial Blood Glucose Control
نویسندگان
چکیده
منابع مشابه
Postprandial blood glucose. American Diabetes Association.
I ndividuals with diabetes are at increased risk of developing microvascular complications (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD). The Diabetes Control and Complications Trial (DCCT) (1) and U.K. Prospective Diabetes Study (UKPDS) (2) showed that treatment programs resulting in improved glycemic control, as measured by HbA1c, reduced the microvascular compli...
متن کاملDoes postprandial blood glucose matter and why?
Type 2 diabetes is characterized by a gradual decline in insulin secretion in response to nutrient loads; hence, it is primarily a disorder of postprandial glucose (PPG) regulation. However, physicians continue to rely on fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) to guide management. There is a linear relationship between the risk of cardiovascular (CV) death and the 2-ho...
متن کاملAdding GLP-1 Receptor Agonist Therapy to Basal Insulin for Postprandial Glucose Control
E ven with current guidelines, treatment algorithms, and recommendations available regarding diabetes management (1,2), providers struggle with adding therapies to manage postprandial hyper-glycemia after basal insulin therapy in combination with oral antidia-betic medications (OADs) has failed to control a patient's hyperglycemia. Historically, after titration of basal insulin to achieve morni...
متن کاملParameters affecting postprandial blood glucose: effects of blood glucose measurement errors.
BACKGROUND The Diabetes Error Test Model (DETM) has been developed to characterize the clinical relevance of the large and varying margins of error of parameters affecting postprandial blood glucose (BG) levels, which increase the risk for hypo- or hyperglycemia. METHODS The DETM is based on a treatment concept aimed at normoglycemia after meals. The model includes as parameters (a) preprandi...
متن کاملEffects of pramlintide on postprandial glucose excursions and measures of oxidative stress in patients with type 1 diabetes.
OBJECTIVE Oxidative stress has been shown to be increased in the postprandial period in patients with diabetes and has been implicated in the pathogenesis of micro- and macrovascular complications. The aim of this post hoc analysis was to assess the effects of pramlintide, an amylin analog shown to reduce postprandial glucose excursions in patients with diabetes, on markers of oxidative stress ...
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ژورنال
عنوان ژورنال: Diabetes Spectrum
سال: 2007
ISSN: 1040-9165,1040-9165
DOI: 10.2337/diaspect.20.2.108